Health Care Rounds

#115: Dissecting the PBM Model with Karthik Ganesh

Episode Summary

This week on Health Care Rounds, John speaks with Karthik Ganesh, CEO of EmpiRx Health and well known thought leader. In this episode, Karthik unpacks the true meaning of value in health care followed by a deep analysis of the PBM model and why it works. They also discuss Karthik’s book, The Happiness Model: A Roadmap to Inner Peace, and what gave him his underlying motivation to share his perspective.

Episode Notes

Karthik Ganesh is the CEO at EmpiRx Health, the industry’s only value-based PBM, with a clinically- focused and tech-enabled approach to bending the Rx cost curve. Prior to EmpiRx Health, Karthik was the founding operations leader of CareAllies. Karthik is a senior health care executive with a solid track record of comprehensively scaling, transforming and maximizing value at tech-enabled health service companies while driving dramatic before-and-after results across all facets of the organization. Karthik is recognized as a thought leader on healthcare, leadership, and resilience. He is a published author and has been featured in leading industry journals.


John Marchica, CEO, Darwin Research Group

John Marchica is a veteran health care strategist and CEO of Darwin Research Group, a health care market intelligence firm specializing in health care delivery systems. He’s a two-time health care entrepreneur, and his first company, FaxWatch, was listed twice on the Inc. 500 list of fastest-growing American companies. John is the author of The Accountable Organization and has advised senior management on strategy and organizational change for more than a decade.


John did his undergraduate work in economics at Knox College, has an MBA and M.A. in public policy from the University of Chicago, and completed his Ph.D. coursework at The Dartmouth Institute. He is a faculty associate in the W.P. Carey School of Business and the College of Health Solutions at Arizona State University and is an active member of the American College of Healthcare Executives.


About Darwin Research Group

Darwin Research Group Inc. provides advanced market intelligence and in-depth customer insights to health care executives, with a strategic focus on health care delivery systems and the global shift toward value-based care. Darwin’s client list includes forward-thinking biopharmaceutical and medical device companies, as well as health care providers, private equity, and venture capital firms. The company was founded in 2010 as Darwin Advisory Partners, LLC and is headquartered in Scottsdale, Ariz. with a satellite office in Princeton, N.J.